|
KMID : 1134819960250060963
|
|
Journal of the Korean Society of Food Science and Nutrition
1996 Volume.25 No. 6 p.963 ~ p.968
|
|
|
Effects of Raw Soy Flour and Magnesium on Serum Glucose and Lipid Metabolism in Streptozotocin - Diabetic Rats
|
|
Koh Jin-Bog
|
|
|
Abstract
|
|
|
|
Effects of raw soy flour(RSF) and RSF with magnesium supplementation (RSF+Mg) feeding on lipid metabolism and serum glucose concentration of diabetic and nondiabetic rats were studied. Male rats(Sprague-Dawley, body weight 332.8±19.3g) were assigned to four dietary groups and fed for 4 weeks. For each experimental diet some rats were injected with streptozotocin in intraperitonium (i.p.) to induce diabetes, and other rats were injected with buffer i.p. as a nondiabetic group. The diabetic rats fed diets of control, RSF and RSF+Mg showed significant body weight decrease(-67~-79g) compared with nondiabetic group. Pancreas weights in diabetic RSF and RSF+Mg groups were heavier than those of the control and nondiabetic groups. Fasting serum glucose level of diabetic RSF and RSF+Mg groups significantly decreased by 73 and 44% compared with the diabetic control group, but they significantly increased by 77 and 111% compared with the nondiabetic group. Serum triglyceride, phospholipid and total cholesterol concentration of diabetic RSF and RSF+Mg groups significantly decreased compared with the diabetic control group. Serum HDL-cholesterol, HDL-cholesterol/toal cholesterol ratio and liver total cholesterol were not affected by RSF and RSF+Mg feeding. Liver total lipid and triglyceride concentration were significantly lower in diabetic groups than those in the nondiabetic group. The results indicated that RSF and RSF+Mg feeding did not produce hyperlipemia and somewhat improved the glucose levels in diabetic rats.
|
|
|
KEYWORD
|
|
|
raw soybean, magnesium, serum lipids, liver lipids, streptozotocin diabetic rats
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|